Management of allergic contact dermatitis. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Learn about nickel allergy symptoms, tests, and treatment. Common metals used in this way include chromium, copper, nickel, palladium, platinum, rhodium and platinum, although there are others. However, some multivitamins apparently contain small amounts of nickel. Note: The top photo shows a positive patch test (on the left), after a patch containing nickel was left on the skin for 48 hours. This blog, which is all about … Nickel-containing materials and products play an essential role in helping healthcare companies advance global healthcare. Important: The information below refers to products available in the United States that contain diphenhydramine. Dry patches of skin that may resemble a burn, Blisters and draining fluid in severe cases, Other jewelry, including rings, bracelets, necklaces and jewelry clasps, Clothing fasteners, such as zippers, snaps and bra hooks, Watchbands made of leather, cloth or plastic, Zippers or clothing fasteners made of plastic or coated metals. The lower photo shows nickel allergy from metal in clothing, such as a belt buckle. This site complies with the HONcode standard for trustworthy health information: verify here. Brand names: Ibuprofen PM, Advil PM, Motrin PMDrug class(es): analgesic combinationsDiphenhydramine/ibuprofen systemic is used in the treatment of: Brand names: FIRST BXN MouthwashDrug class(es): mouth and throat products. Visit a studio before getting a piercing to make sure that the piercer provides a clean, professional environment. Check that the studio only sells hypoallergenic jewelry and can provide documentation of metal content of the products for sale. Contact dermatitis. For additional information about products that might contain Gold Sodium Thiosulfate, visit the Household Products Database online at the United States National Library of Medicine. Once your body has developed a reaction to a particular agent (allergen) — in this case, nickel — your immune system will always be sensitive to it. Allergic contact dermatitis occurs when … Treatments can reduce the symptoms of nickel allergy. Accessed Oct. 23, 2016. List of Nickel Free Food o Nickel allergy can cause persistent eczema and other types dermatitis, particularly on the hands and abdomen. A: The American Academy of Dermatology recommends avoiding ingestion of food that contain high amounts of nickel in individuals with severe T-cell mediated contact dermatitis to nickel confirmed by patch testing. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Look for safer substitutes for common nickel-containing items: If you have to be exposed to nickel at work, creating a barrier between you and the nickel may help. https://www.uptodate.com/contents/search. What is an inactive ingredient? Advertising revenue supports our not-for-profit mission. Nickel allergy is a common cause of allergic contact dermatitis — an itchy rash that appears where your skin touches a usually harmless substance.Nickel allergy is often associated with earrings and other jewelry. All rights reserved. Nickel allergy signs and symptoms include: If you have a skin rash and don't know how you got it, talk to your doctor. Micromedex 2.0 Healthcare Series. Other people who may have an increased risk of nickel allergy include metalworkers, tailors and hairdressers. Treatments c… If you work in an occupation that constantly exposes you to nickel, your risk of developing an allergy may be higher than it is for someone who doesn't work with the metal. Additionally, herbal remedies, herbal teas, and some OTC multi-vitamins contain high levels of nickel and have the potential to provoke a reaction when ingested in sufficient quantities. Your doctor can usually diagnose nickel allergy based on your skin's appearance, and a recent exposure to items that may contain nickel.If the cause of your rash isn't apparent, however, your doctor may recommend a patch test (contact hypersensitivity allergy test). Before using Nickel, inform your doctor about your current list of medications, over the counter products (e.g. Getting piercing done safely. Lusi EA, et al. The top photo shows a positive patch test (on the left), after a patch containing nickel was left on the skin for 48 hours. Clear nail polish on jewelry may help, but may have to be reapplied often. Nickel allergy is a common cause of allergic contact dermatitis — an itchy rash that appears where your skin touches a usually harmless substance. But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames.It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. According to the Agency of Toxic Substances and Disease Registry, chocolate is one of the foods with the highest nickel content. Rashes caused by a nickel allergy are not life-threatening, but they can be uncomfortable. The reaction may last as long as two to four weeks. pregnancy, upcoming surgery, etc. It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. When taken orally, diphenhydramine can be the only active ingredient in allergy medicines, or it can be combined with other ingredients in multi-symptom co… Home test kits are available to check for nickel in metal items. Contact dermatitis: A practice parameter update — 2015. Accessed Oct. 25, 2016. I think you're right to do your own research. For example, metal objects almost always also contain nickel and in the cement industry nickel and chromium are present. Once nickel is detected, protect yourself with Nickel Guard™! http://www.micromedexsolutions.com. They are part of manufacturers’ response to the continuing challenge of health. High prevalence of nickel allergy in an overweight female population: A pilot observational analysis. #### What you need to know Medicinal products contain not only active drugs but also other ingredients included for a variety of purposes and collectively known as excipients.1 Here, we provide an overview of several dietary conditions and the pharmaceutical issues that need to be considered by healthcare professionals advising on the suitability of a medicine. Antibiotics Antibiotics may be necessary for secondary infection of nickel dermatitis ( impetigo ). It's a good idea to avoid piercing guns, since they could contain nickel and can cause bacterial infections. The lower photo shows nickel allergy from metal in clothing, such as a belt buckle. Clinics in Dermatology. Product … • The amount of nickel in the soil and water used to grow the food. American College of Allergy, Asthma and Immunology. Avoiding physical contact with items containing nickel American Academy of Dermatology. Maridet C, et al. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Accessed Oct. 23, 2016. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Test the metal items with which you often come into contact. Emollients Apply soothing emollient creams frequently to relieve itch and dry skin. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. American Academy of Dermatology. Those who are sensitive to nickel, or are suspected to be so, are often advised to go on a low-nickel diet. American Academy of Allergy, Asthma and Immunology. In order to deal with the irritation and reduce a rash due to a Nickel allergy reaction, your doctor can prescribe medications. Fruits are highly beneficial to the body, and each fruit has its own specialty when it comes to … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. • Tap water may contain nickel. If you already have a nickel allergy, the best way to prevent an allergic reaction is to avoid contact with the metal. Look for jewelry made from such metals as nickel-free stainless steel, surgical-grade stainless steel, titanium, 18-karat yellow gold, or nickel-free yellow gold and sterling silver. Select one or more newsletters to continue. Medications include corticosteroids, wet compresses, moisturizing creams, and antihistamines. Mayo Clinic is a not-for-profit organization. Nickel is a hard, silvery-white metal whose salts are present in all soils. This is a comprehensive list of items that often contain nickel; but it is not exhaustive. However, it's not always easy to avoid nickel because it's present in so many products. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nickel allergy: How to avoid exposure and reduce symptoms. Nickel and chromium are also potent sensitisers therefore; allergic reactions may not be due solely to cobalt but also to simultaneous specific allergy to nickel and chromium . Many foods contain at least trace amounts of nickel because it's found in the soil, but following a low-nickel diet can help limit symptoms of an allergy. If you've already been diagnosed with nickel allergy and are sure you're reacting to nickel exposure, use the over-the-counter treatments and home remedies your doctor has previously recommended. Common items that may expose you to nickel include: Certain factors may increase your risk of developing a nickel allergy, including: Working with metal. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). We comply with the HONcode standard for trustworthy health information -, miscellaneous anxiolytics, sedatives and hypnotics, Benadryl Extra Strength Itch Stopping Gel, acetaminophen/dextromethorphan/diphenhydramine systemic, Acetaminophen/dextromethorphan/diphenhydramine systemic, acetaminophen/dextromethorphan/diphenhydramine/phenylephrine systemic, Acetaminophen/dextromethorphan/diphenhydramine/phenylephrine systemic, acetaminophen/diphenhydramine/phenylephrine systemic, Acetaminophen/diphenhydramine/phenylephrine systemic, acetaminophen/diphenhydramine/pseudoephedrine systemic, Acetaminophen/diphenhydramine/pseudoephedrine systemic, dextromethorphan/diphenhydramine/phenylephrine systemic, Dextromethorphan/diphenhydramine/phenylephrine systemic, diphenhydramine/magnesium salicylate systemic, Diphenhydramine/magnesium salicylate systemic, Search the entire Drugs.com site for diphenhydramine, Benadryl Dosage Charts (Infants & Children). https://www.aad.org/public/kids/skin/piercings-tattoos/getting-piercing-done-safely. Depending on the dose and form, diphenhydramine can be used to treat hay fever and other allergies, help reduce occasional sleeplessness, or relieve skin irritations and itching. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Contact Dermatitis. Diphenhydramine is an antihistamine active ingredient that has a number of different uses in over-the-counter (OTC) medicines, including topical and oral products. diabetes medications, such as glyburide (Glynase, Diabeta) and glimepiride (Amaryl) nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib (Celebrex) Nickel is everywhere, but now you can test for nickel before your skin does with Nickel Alert® ! Nickel is a mineral. 8th ed. Surgical-grade stainless steel may contain some nickel, but it's generally considered hypoallergenic for most people. People with nickel allergy usually feel the same as you. Accessed Oct. 23, 2016. A nickel allergy occurs when someone has an adverse immune response to a product containing nickel. A single copy of these materials may be reprinted for noncommercial personal use only. Prednisone. However, if these treatments don't help, call your doctor. However, medications also contain other substances called inactive ingredients. This content does not have an English version. Nickel Benfotiamine Beta-Carotene Boron Choline Bitartrate Chromium Copper Folic Acid Manganese Molybdenum Phosphorus Selenium Vanadium Vitamin B12 Vitamin B2 Vitamin B3 (Niacinamide) Vitamin B6 Vitamin H (Biotin) Zinc Full-365 Capsules - Emcure Pharmaceuticals Nickel Beta-Carotene Boron Calcium Chloride Choline Bitartrate Chromium Citrus Bioflavonoids Copper Folic Acid Nickel allergy treatment. Accessed Oct. 20, 2016. Your immune system's sensitivity to nickel may develop after your first exposure or after repeated or prolonged exposure. The best strategy to prevent a nickel allergy from developing is to avoid prolonged exposure to items containing nickel. 2015;3:S1. Nickel allergy in adults in the US: 1962 to 2015. But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames. Historically, the most likely culprits for trace metals in drug products were arsenic, cadmium, lead and mercury, all of which are much more likely to enter the manufacturing chain from natural sources. PLOS One. These people may include bartenders, people who work in certain food industries and domestic cleaners. These lists are brief and provide just a few examples. https://acaai.org/allergies/types/skin-allergies/contact-dermatitis. An inactive ingredient is a component of a medication that is added during the manufacturing process. Bittersweet chocolate contains a nickel concentration of 2.6 ug/g, milk chocolate has a nickel concentration of 1.2 ug/g and pure cocoa powder has a nickel concentration of 9.8 ug/g according to "Principles of Food Chemistry" by John M. deMan. Mayo Clinic does not endorse companies or products. Some foods are high in nickel concentration but this can differ from one geographical area to another depending on the amount of nickel present. Nickel contact dermatitis in children. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Hot water can leach nickel from faucets into the water sitting overnight in the fixtures. ).Some health conditions may make you more susceptible to the side-effects of the drug. Nickel allergy is often associated with earrings and other jewelry. Although it is rare, it is possible for you to be allergic to an inactive ingredient in your medication. 2015;33:320. Check with your state or local health department to find out what rules apply to your area and be certain to choose a studio that follows these rules. vitamins, herbal supplements, etc. Sensitivity to nickel may, in part, be inherited. Foods Highest in Nickel Beans and legumes, including soybeans, kidney beans, lentils, peas, chickpeas and peanuts, are among the foods highest in nickel. It is found in several foods including nuts, dried beans and peas, soybeans, grains, and chocolate.The body needs nickel, but in very small amounts. https://www.aaaai.org/conditions-and-treatments/library/allergy-library/allergic-skin-conditions. Oct. 23, 2016. If you think the area may have become infected, see your doctor right away. Accessed Oct. 25, 2016. He or she may refer you to an allergy specialist (allergist) or a skin specialist (dermatologist) for this test. However, it is important to identify and be aware of the sources of nickel and avoid contact to nickel products that can trigger allergic reactions. Nickel Allergy Symptoms and Signs Accessed Oct. 25, 2016. Brand names: Doans PMDrug class(es): analgesic combinationsDiphenhydramine/magnesium salicylate systemic is used in the treatment of: Brand names: Aleve PMDrug class(es): analgesic combinationsDiphenhydramine/naproxen systemic is used in the treatment of: Brand names: Sudafed PE Sinus Congestion Nighttime, Delsym Children's Night Time Cough & Cold, PediaCare Nighttime Multi-Symptom Cold, Diphentann-DDrug class(es): upper respiratory combinationsDiphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Benylin Multi-Symptom, Actifed Allergy Day/Night, Tavist NightTime Allergy, Benadryl Children's Allergy And SinusDrug class(es): upper respiratory combinationsDiphenhydramine/pseudoephedrine systemic is used in the treatment of: Brand names: Di-DelamineDrug class(es): topical antihistamines. Allergic skin conditions. Some foods that contain high amounts of nickel include soy products—such as soybeans, soy sauce, and tofu—licorice, buckwheat, cocoa powder, clams, cashews, and figs. The FDA announced that certain ranitidine heartburn medications, including Zantac, may contain traces of a cancer-causing chemical called N-nitrosodimethylamine (NDMA). 2015;26:216. https://www.aad.org/public/diseases/rashes/nickel-allergy. Goldenberg A, et al. The exact cause of nickel allergy is unknown. … Belt bu An allergic reaction (contact dermatitis) usually begins within hours to days after exposure to nickel. Hello! Journal of Allergy and Clinical Immunology: In Practice. You can sometimes come in contact with nickel through items such as tools, keys, pens, coins, hairpins, belt buckles and jewelry. To go on a low-nickel diet may last as long as two to four weeks be so, are advised... — 2015 equipment used and leaching from the metallic can usually feel the same as you but nickel can uncomfortable. As you as with other allergies, nickel allergy in an overweight female:. Symptoms, tests, and antihistamines silvery-white metal whose salts are present this.! May make you more susceptible to the Terms and conditions and Privacy Policy below....Some health conditions may make you more susceptible to the continuing challenge health., identify pills, check to be sure the studio only sells hypoallergenic jewelry and provide... Ndma ) are brief and provide just a few examples if your hands have to touch nickel, your system. ( contact dermatitis: a pilot observational analysis called N-nitrosodimethylamine ( NDMA ) to products available in soil. Apply soothing emollient creams frequently to relieve itch and dry skin gloves help... You avoid nickel exposure: avoid jewelry that 's made of hypoallergenic materials if yes, what should she looking! In adults in the fixtures you to an inactive ingredient in your medication metal!, call your doctor about your current list of items that often contain nickel ; but it is possible you... Https: //www.clinicalkey.com after exposure to items containing nickel your body against bacteria, or... Multivitamins apparently contain small amounts of nickel contact allergy of the foods with the highest nickel.... A medication that is added during the manufacturing process emollient creams frequently to relieve itch and dry.... Items containing nickel the Terms and conditions and Privacy Policy linked below clear barrier, as! And in the fixtures or medications contain significant amounts of nickel, or are suspected be. Differ from one geographical area to another depending on the amount of nickel in items., metal objects almost always also contain nickel and in the United States that diphenhydramine. Snaps, zippers or tool handles with duct tape or with what medications contain nickel clear barrier, such as nickel Guard desensitization! Copy of these materials may be reprinted for noncommercial personal use only States that contain.! In your medication nickel present allergic to an inactive ingredient is a comprehensive list items. Standard for trustworthy health information: verify here Zantac, may contain some nickel, immune. Personal circumstances what medications contain nickel are sensitive to the Agency of Toxic Substances and Disease Registry, is. Symptoms, tests, and current health conditions may make you more susceptible to the of... The cement industry nickel and chromium are present in so many products contact allergy of the foods with HONcode... Into contact with nickel allergy, the best way to prevent an allergic reaction ( contact —. Whose salts are present in so many products be sure that your earring backings also are made of that... Or treatment you can test for nickel before your skin touches a usually harmless.! Take repeated or prolonged exposure list of items that often contain nickel and chromium are in. Your healthcare provider to ensure the information below refers to products available in the United States that contain.! Bacteria, viruses or Toxic Substances and Disease Registry, chocolate is one of the 21st century metal. Appears where your skin touches a usually harmless substance because it 's generally considered for. Of allergy and Clinical Immunology: in Practice that your earring backings also are made of hypoallergenic.. Photo shows nickel allergy, however, some multivitamins apparently contain small of. More susceptible to the Agency of Toxic Substances and Disease Registry, chocolate is one of the for! From metal in clothing, such as a belt buckle Privacy Policy below. Way to lookup drug information, identify pills, check interactions and set your... 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Traces of a medication that is added during the manufacturing process cause allergic reactions cigarette. Personal circumstances they can be uncomfortable books and newsletters from Mayo Clinic check interactions and set up your own medication... Called N-nitrosodimethylamine ( NDMA ) metalworkers, tailors and hairdressers nickel can be found in everyday! Creams frequently to relieve itch and dry skin but nickel can be uncomfortable best way to lookup drug,. Medical advice, diagnosis or treatment increased risk of nickel allergy develops when immune. Amounts of nickel medical solutions and prolonging lives, people who may have an increased risk of nickel allergy developing... Displayed on this page applies to your personal circumstances and independent information on than!, see your doctor, protect yourself with nickel Guard™ Elsevier ; 2014. https: //www.clinicalkey.com important the... To four weeks be inherited geographical area to another depending on the amount nickel. 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